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Smyth
The sodium iodide symporter and thyroid disease.Smyth PP, Dwyer RM. Clin Endocrinol (Oxf). 2002 Apr;56(4):427-9. Review.
"The discovery of the NIS gene has dramatically increased the potential for understanding pathways involved in iodide transport both in the thyroid and extrathyroidally. Greater understanding of these pathways offers the possibility not only for studying iodide transport but also the previously unknown potential extrathyroidal roles for iodine. It also offers the exciting prospect of applying the findings to the effective use of radioiodines as diagnostic or systemic therapeutic agents in a variety of cancers."
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