Home | Orthoiodosupplementation | Body | Disease | Special | Overviews

Special Topics

Physiology

Transporters

NIS

• Abraham

• Ajjan, Kilbane, Weetman

• Carrasco

• Colorado SU

• Costagliola

• Elisei

• Endo

• Ferreira

• Filetti

• Fujiwara

• Furlanetto

• Gene Reports

• Heufelder

• Josefsson

• Jhiang

• Kim, Chung

• Kogai

• Kotani

• Lim, Moon

• Mitchell

• Mitrofanova

• Pekary

• Perron

• Riesco-Eizaguirre

• Rhoden

• Schlumberger

• Schmitt

• Smyth

• Spitzweg

• Suzuki

• Tazebay

• Tonacchera

• Upadhyay

• Van Sande

• Venkataraman

• Yoshida, Kosugi

• Wapnir

• Wolff

Mitchell

Sodium iodide symporter (NIS) gene expression in human placenta.

Mitchell AM, Manley SW, Morris JC, Powell KA, Bergert ER, Mortimer RH.

Placenta. 2001 Feb-Mar;22(2-3):256-8.

"The placenta must allow the passage of iodide from the maternal to the fetal circulation for synthesis of thyroxine by the fetal thyroid. The thyroid sodium iodide symporter (NIS) was cloned in 1996 and, although widely distributed among epithelial tissues, early studies failed to detect it in placenta. We demonstrated NIS mRNA in human placenta and in the human choriocarcinoma cell line, JAr. NIS protein was localized to trophoblasts, with a tendency to apical distribution, in sections of human placenta immunostained with a monoclonal antibody against hNIS. We conclude that NIS is expressed in placenta and may mediate placental iodide transport. "

 Home | Orthoiodosupplementation | Body | Disease | Special Topics | Overviews  

The Iodine Group | Books | Disclaimers | Contact Us | Search  

  Copyright: Zoe, 2006.