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Iodine Absorption

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Nelson

The absorption, excretion, and physiological effect of iodine in normal human subjects.

Nelson N, Palmes ED, Park CR, Weymouth PP, Bean WB.

J Clin Invest. 1947 Mar;26(2):301-10.

"(1) Inorganic iodine was rapidly and completely absorbed from the gastrointestinal tract.

(2) The plasma concentration of iodine was directly proportional to the quantity ingested.

(3) The iodine plasma level fell rapidly after cessation of iodine intake reaching near basal levels within 72 hours.

(4) Excretion of iodine was chiefly in the urine but an appreciable fraction appeared in the sweat. Sweat iodine concentration was 35 per cent of plasma concentration. Fecal excretion was negligible.

(5) No effect on general health, acclimatization to heat, vital signs, basal metabolism, blood, or urine could be ascribed to the ingestion of iodine by normal subjects over a period of 6 weeks.

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