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IODINE ABSORPTION
One of the fundamental issues to understand is how iodine enters the body. There seem to be two primary methods: the skin (transdermal) and the mouth (oral).
But so far, very little is understood about how this process of absorption takes place. For example, what happens to the various iodine products as they enter the mouth, the stomach, the intestines, the blood stream? When someone swallows a drop of Lugol's solution, how much molecular iodine ends up in the blood stream? What other iodine forms are created?
Similarly, when tincture of iodine is painted on the skin and it gradually disappears, what is actually happening? How much is evaporating? How much is being absorbed? What forms are being absorbed and how?
Many people use the Iodine Patch Test for assessing whether they have enough iodine. However, when painting iodine on the skin, what is actually happening to the iodine? Does the amount of iodine in the body (or in the skin) affect what happens to the painted iodine?
Similarly, many women with breast problems are now painting their breasts with iodine. What happens to that iodine? How much of it, in what form, is absorbed? Once it is absorbed, where does it go? How much stays in the breast and how much gets circulated in the blood stream?
Nyiri wrote an article in 1932 attempting to understand transdermal absorption. It is often quoted to prove that little iodine is absorbed. What he actually proved was that iodine is one of the substances that CAN be absorbed through the skin.
Gottardi made the startling observation that the residual effect of iodine-based disinfectants is caused by a dynamic back-diffusion. Not only is iodine being absorbed through the skin, it is also diffused back out of the skin.
Tomoda is one of several to study the transcutaneous absorption of povidone-iodine during surgery or other circumstances.
Arena, Delange, and Vorherr are among those to study vaginal absorption of iodine.
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