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FOSTER

Landscapes of longevity: the calcium-selenium-mercury connection in cancer and heart disease.

Foster HD.

Med Hypotheses. 1997 Apr;48(4):355-60. Review.

[abstract only]

"Cancer and heart disease display spatial patterns that suggest the possible involvement of calcium and selenium deficiencies and mercury excess in their aetiologies. As a consequence, longevity tends to be most common in regions where the environment is calcium- and selenium-enriched but contains only low levels of mercury. Examples are cited from West Africa, China, England and the USA."

Longevity and selenium deficiency: evidence from the People's Republic of China.

Foster HD, Zhang L.

Sci Total Environ. 1995 Aug 18;170(1-2):133-9.

[abstract only]

"Data were abstracted from the Atlas of Aged Population in the People's Republic of China and from The Atlas of Endemic Diseases and their Environments in the People's Republic of China. The spatial distribution of the elderly, those aged 80 years or more in 1982, in 2408 counties, was then compared with the prevalences of Kaschin-Beck and Keshan diseases, both of which involve extreme selenium deficiency. Pearson chi-square, the Mantel-Haenszel test for linear, association and Spearman correlation all clearly indicate that the elderly in China are not normally distributed. Far fewer people of advanced age reside in those counties in which Kaschin-Beck and Keshan diseases are endemic than in unaffected counties. The possible reasons for this are thought to include elevated mortality from endemic and chronic diseases in selenium deficient areas and accelerated ageing due to excessive cellular damage caused by free radicals. These two phenomena may be related."
 

The iodine-selenium connection: its possible roles in intelligence, cretinism, sudden infant death syndrome, breast cancer and multiple sclerosis.

Foster HD.
Med Hypotheses. 1993 Jan;40(1):61-5. Review.

“Several diseases and disorders display spatial patterns that suggest the involvement of both selenium and iodine deficiencies, or excesses, in their etiologies. It is suggested that many of these similarities in geographical distribution occur because both elements influence thyroid hormone metabolism.”

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