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Fort
Breast and soy-formula feedings in early infancy and the prevalence of autoimmune thyroid disease in children.Fort P, Moses N, Fasano M, Goldberg T, Lifshitz F. J Am Coll Nutr. 1990 Apr;9(2):164-7. [abstract only]
"It has been suggested
that feeding practices in infancy may affect the development of
various autoimmune diseases later in life. Since thyroid
alterations are among the most frequently encountered autoimmune
conditions in children, we studied whether breast and
soy-containing formula feedings in early life were associated
with the subsequent development of autoimmune thyroid disease. A
detailed history of feeding practices was obtained in 59 children
with autoimmune thyroid disease, their 76 healthy siblings, and
54 healthy nonrelated control children. There was no difference
in the frequency and duration of breast feeding in early life
among the three groups of children. However, the frequency of
feedings with soy-based milk formulas in early life was
significantly higher in children with autoimmune thyroid disease
(prevalence 31%) as compared with their siblings (prevalence 12%;
chi 2 = 7.22 with continuity factor; p less than 0.01), and
healthy nonrelated control children (prevalence 13%, chi 2 = 5.03
with continuity factor; p less than 0.02). Therefore, this
retrospective analysis documents the association of soy formula
feedings in infancy and autoimmune thyroid disease." |
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