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Thyroid Disease

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KASAGI

Effect of iodine restriction on thyroid function in patients with primary hypothyroidism.

Kasagi K, Iwata M, Misaki T, Konishi J.

Thyroid. 2003 Jun;13(6):561-7.

“Dietary iodine intake in Japan varies from as little as 0.1 mg/day to as much as 20 mg/day. The present study was undertaken to assess the frequency of iodine-induced reversible hypothyroidism in patients diagnosed as having primary hypothyroidism, and to clarify the clinical backgrounds responsible for the spontaneous recovery of thyroid functions…. In conclusion, (1) primary hypothyroidism was recovered following iodine restriction in more than half of the patients, and (2) the reversibility of hypothyroidism was not significantly associated with Hashimoto's thyroiditis but with increased (99m)Tc uptake and elevated non-hormonal iodine levels.”

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