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Thyroid Physiology  

Thyroid Disease

 

Goiter

 

ABRAHAM

 

The concept of orthoiodosupplementation and its clinical implications.

Abraham, GE

The Original Internist, 11(2):29-38, 2004

 

"Elevated TSH induces hypertrophy, whereas intrathyroidal iodine deficiency induced thyroid hyperplasia. In iodine-deficient goiter, iodine supplementation abolishes not only hypertrophy, but also hyperplasia of the thyroid gland. On the other hand, suppression of TSH with T4 abolishes hypertrophy, not hyperplasia if there is intrathyroidal iodine deficiency. Therefore, administration of T4 to iodine-deficient patients does not decrease their risk for thyroid cancer, an effect expected with iodine supplementation."

 

 

A Rebuttal of Dr. Gaby's Editorial on Iodine

Guy E. Abraham, MD and David Brownstein, MD 

Townsend Letter for Doctors & Patients, October 2005

 

"One of the most satisfying effects of orthoiodosupplementation has been in the treatment of fibrocystic breasts and thyroid nodules. The treatment of fibrocystic breasts with iodine has been reported for over 100 years. Iodine/iodide supplementation has resulted in significant improvement in fibrocystic breast illness for nearly every patient treated. Thyroid nodules also respond positively to iodine/iodide supplementation. Serial ultrasounds usually show decrease in the size of the thyroid cysts and nodules and eventual resolution of the lesions. When orthoiodosupplementation is combined with a complete nutritional program, it is rare not to see improvement in the palpation and radiological examination of thyroid nodules and cysts following iodine/iodide therapy as described here."
 

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