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Lung Cancer

• Bakheet, Hammami

• Fernandez-Ulloa

• Lejeune

• Misaki

• Sohn

• Zhang

Misaki

Radioiodine uptake by squamous-cell carcinoma of the lung.

Misaki T, Takeuchi R, Miyamoto S, Kasagi K, Matsui Y, Konishi J.

J Nucl Med. 1994 Mar;35(3):474-5.

"A patient with a history of total thyroidectomy for papillary carcinoma showed a solitary hot spot in the chest on post-therapy radioiodine imaging. Subsequent evaluation demonstrated that this lesion was a primary squamous-cell lung cancer. Our case illustrates a rare but important differential diagnosis from lung metastasis of thyroid cancer in 131I scintigraphy. Alternatively, this "aberrant uptake" might be a rather common phenomenon for lung neoplasms, although the underlying mechanism is not yet known. Future experimental studies might lead to a new application of radioiodine imaging in pulmonary oncology."

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