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Iodine and the Body

 

Mouth

Exocrine Glands

IODINE AND THE MOUTH

 

Iodine is concentrated in the salivary glands via the NIS symporter.  Exactly what happens to this iodine is not yet fully understood.

 

Radioactive iodine concentrates in the salivary gland, causing undesirable side effects from RAI treatment.

 

Iodine is commonly used as a disinfectant for periodontal conditions.

 

Iodine may also be involved in tooth formation, with fluoride being taken up by mechanisms intended for iodine uptake.

 

 

Venturi discusses iodine evolution and how the salivary glands came to have high iodine-concentrating capacity via an efficient NIS.  He states that the salivary glands and gastric mucosa have the ability to concentrate iodides, as well as to form iodocompounds by peroxidases.

 

Venturi believes that the antioxidant, apoptosis-inductor and presumed antitumor activities of iodide might be useful in oral health and in prevention of  salivary gland cancers.

 

Spitzweg analyzes human sodium iodide symporter gene expression in extrathyroidal tissues, including the salivary gland.

 

Mandel discussed the process of concentrating iodine in the salivary glands, thus exposing them to the damaging effects of irradiation from radioactive iodine.

 

Jorgensen discusses povidone-iodine as a periodontal pocket disinfectant.

 

Derry suggests that iodine is important in teeth and bones, especially when they are growing.  Fluoride is taking the place of the iodine that should be in the teeth.

 

 

More articles on salivary glands under exocrine glands.

 

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  Copyright: Zoe, 2006.