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Iodine and the Body

 

Iodine and Eyes

 

Exocrine Glands

Becker

 

Iodide transport by the rabbit eye.

Becker B

Am J Physiol. 1961 Apr;200:804-6.

[abstract only]

 

"I131 is accumulated by rabbit ciliary body-iris preparations in vitro and transported out of the living rabbit eye. The secretory system resembles the accumulation of iodide by the thiouracil-treated thyroid gland. It is saturated by iodide and inhibited by perchlorate, thiocyanate and fluoroborate. The mechanism for iodide transport out of the rabbit eye appears to be independent of the analogous transport of iodopyracet and related organic anions."

 

 

The turnover of iodide in the rabbit eye.

Becker B

Arch Ophthalmol. 1961 Jun;65:832-6.

[citation only]

 

 

Cerebrospinal fluid iodide.

Becker B

Am J Physiol. 1961 Dec;201:1149-51.

[abstract only]

 

"In vitro preparations of rabbit choroid plexus accumulated I131 to a concentration 20–30 times the media. The accumulation was temperature dependent and was blocked by metabolic inhibitors. It could also be saturated with iodide, and was inhibited by perchlorate, fluoroborate, and related anions. In vivo the low 4-hr steady state concentration (1.6% of plasma) of trace doses of I131 in the rabbit cerebrospinal fluid was increased (to 40% of plasma) by the systemic administration of iodide or perchlorate. The results resembled qualitatively those obtained in the vitreous and aqueous humors of the same animals and suggested an active transport of iodide out of the cerebrospinal fluid, much as postulated previously for ocular fluids."

 

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