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Iodine and the Body

 

Iodide and Brain (CNS)

ANDRASI

 

Determination of iodine in human brain by epithermal and radiochemical neutron activation analysis

Andrasi E, Kucera J, Belavari C, Mizera J

Microchemical Journal 2007.  85: 157-163.

 

"Despite the role of iodine for proper development of the brain and the functions of the element, the accurate data on its concentration in brain tissue are largely lacking, the main reason being analytical difficulties associated with determination of the element especially at low levels.  In this work, samples from human brain regions from Hungarian patients were analyzed using epithermal and radiochemical neutron activation analysis (ENAA and RNAA, respectively).  The RNAA procedure is based on alkaline-oxidative fusion followed by extraction of elemental iodine in chloroform.  The results were checked by the analysis of biological standard reference materials, namely bovine liver, bone meal and diet, and by comparison with previous results obtained by a different RNAA procedure."

 

 

Iodine concentration in different human brain parts.

Andrasi E, Belavari C, Stibilj V, Dermelj M, Gawlik D.

Anal Bioanal Chem. 2004 Jan;378(1):129-33. Epub 2003 Nov 13.

[abstract only]

 

"Iodine is one of the most important essential elements as demonstrated by the fact that its deficiency can cause goitre. Nevertheless, quantitative data on its concentration in biological materials, especially in the human brain, are scarce. There is therefore a demand for accurate and reliable information on iodine in these types of samples. The purpose of the present work was to determine the concentration of total iodine in some control human brain parts by rapid radiochemical neutron activation analysis. Our second goal was to determine I distribution between lipid fraction and in brain tissue without lipid by applying two types of solvent extraction methods. The results were checked by the analysis of biological standard reference materials with certified or literature values for iodine and good agreement was found."

 

 

Normal Human Brain Analysis.

E Andrasi, L Orosz, L Bezur, L Ernyei, Z Molnar

Microchemical J, 1995.  pp. 99-105.

[citation only]

 
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